The SHIELD database is a resource for dissemination and comparison of inner-ear gene expression datasets, initially developed by laboratories associated with Harvard Medical School and now including Creighton University School of Medicine, Oregon Health & Science University and Rutgers University. Expression data are available for online viewing for individual genes for all datasets (Gene Search) and may be downloaded for all genes for individual published datasets (Datasets). Some data are not yet published, but are made available as a service to the auditory and vestibular research community. Please contact us if you would like to have your related research datasets integrated into the SHIELD. Thank you!


For the database in general, please cite: Shen J, Scheffer DI, Kwan KY, Corey DP. SHIELD: an integrative gene expression database for inner ear research. Database (Oxford). 2015. doi: 10.1093/database/bav071. (PMID: 26209310). For individual datasets, please see Datasets.


07/24/2015 • The paper describing the SHIELD is published in Database (Oxford).

04/22/2015 • The dataset of FACS sorted hair cells is now published in the Journal of Neuroscience and can be downloaded.

04/08/2015 • SHIELD helped a new study of hair cell development and function published in the Journal of Neuroscience.

03/27/2015 • SHIELD facilitated the identification of a new nonsyndromic deafness gene, published in PLoS Genetics .