MOUSE GENE INFORMATION [PubMed]
| Description | collagen, type IX, alpha 2 | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Synonyms | Col9a-2 | ||||||||||||
| Chromosome | 4 | ||||||||||||
| Genetic Map Distance | 56.78 cM | ||||||||||||
| RefSeq Accessions | NM_007741; NP_031767 | ||||||||||||
| NCBI Entrez Gene | 12840 at chr4:120712171-120727930 (mm9) / chr4:121039566-121055325 (mm10) | ||||||||||||
| Ensembl Gene | ENSMUSG00000028626 | ||||||||||||
| VEGA Gene | OTTMUSG00000008902 | ||||||||||||
| MGI Gene | MGI:88466 | ||||||||||||
| Mouse Protein (2) |
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| Pfam Domains | Collagen; Collagen; Collagen; Collagen; Collagen; Pfam-B_544; Collagen; Pfam-B_5239; Collagen; Collagen; Collagen; Pfam-B_5239; Collagen | ||||||||||||
| Mouse alleles (3) |
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| Human Homolog | COL9A2 (collagen, type IX, alpha 2) | ||||||||||||
| Human synonyms | DJ39G22.4; EDM2; MED; STL5 | ||||||||||||
| Human cytoband | 1p33-p32 | ||||||||||||
| Known deafness gene | No | ||||||||||||
| Within mapped deafness loci | No | ||||||||||||
| Associated Human Disease in OMIM | |||||||||||||
| Chicken homolog (0) |
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Gene Ontology
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FACS-Sorted Hair Cells
Data |
Chart
E16a |
E16b |
P0 |
P4 |
P7 |
P16 |
|
|---|---|---|---|---|---|---|
Utricle GFP+ cells |
6883 |
3580 |
2520 |
1214 |
3620 |
640 |
Cochlea GFP+ cells |
1636 |
8188 |
2691 |
2654 |
2179 |
NA |
Utricle GFP- cells |
2245 |
5038 |
11904 |
9236 |
13979 |
3319 |
Cochlea GFP- cells |
1969 |
3110 |
8581 |
8863 |
13993 |
NA |
Analysis
Condition A |
Mean A |
Condition B |
Mean B |
Fold Change (B/A) |
False Discovery Rate (FDR) |
|---|---|---|---|---|---|
GFP- |
7476 |
GFP+ |
3255 |
0.44 |
0.394 |
Utricle |
5348 |
Cochlea |
5386 |
1.01 |
1 |
Embryonic |
4081 |
Postnatal |
6100 |
1.49 |
0.647 |
Adult Cochlear Inner and Outer Hair Cells
| Probeset ID | IHC (mean ± sd) | OHC (mean ± sd) [OHC replicate] | Fold Change (OHC/IHC) | False Discovery Rate (FDR) |
|---|---|---|---|---|
| 17418059 | 49.87 ± 3.13 | 59.68 ± 7.34 [51.57] | 1.20 | 0.519 |
Otic Progenitor Cells
Data
Growth Factor |
Replicate 1 |
Replicate 2 |
Replicate 3 |
Mean |
|---|---|---|---|---|
bFGF |
14 |
17 |
35 |
18 |
No bFGF |
65 |
78 |
77 |
160 |
EGF |
64 |
83 |
90 |
79 |
Analysis
Condition A |
Mean A |
Condition B |
Mean B |
Fold Change (B/A) |
False Discovery Rate (FDR) |
|---|---|---|---|---|---|
bFGF |
18 |
No bFGF |
160 |
8.60 |
0.00067 |
bFGF |
18 |
EGF |
79 |
4.28 |
3.5e-8 |
No bFGF |
160 |
EGF |
79 |
0.50 |
3.7e-6 |
Chicken Stereocilium Proteomics
No chicken homolog has been identified for Col9a2.
Auditory and Vestibular Ganglion Neurons
Probe set ID: 1450673_at
| Age | E12 | E13 | E16 | P0 | P6 | P15 |
|---|---|---|---|---|---|---|
| Spiral ganglion | ||||||
| Replicate 1 | 27.54 | 13.65 | 28 | 26.68 | 818.59 | 180.37 |
| Replicate 1 Call | A | A | A | A | P | P |
| Replicate 2 | 17.24 | 8.76 | 26.44 | 85.6 | 116.76 | 53.26 |
| Replicate 2 Call | A | A | A | A | A | A |
| Replicate 3 | 22.81 | 16.2 | 32.32 | 32.12 | 1391.44 | 53.41 |
| Replicate 3 Call | A | A | A | A | P | A |
| Replicate 4 | 34.49 | 27.26 | 1364.81 | 26.3 | ||
| Replicate 4 Call | A | A | P | A | ||
| Mean | 22.53 | 12.87 | 30.31 | 42.92 | 922.9 | 78.34 |
| Standard Deviation | 5.16 | 3.78 | 3.73 | 28.56 | 598.76 | 69.21 |
| Log2 Mean | 4.47 | 3.64 | 4.91 | 5.23 | 9.35 | 5.92 |
| Log2 Standard Deviation | 0.34 | 0.46 | 0.18 | 0.8 | 1.69 | 1.15 |
| Vestibular ganglion | ||||||
| Replicate 1 | 20.15 | 46.75 | 53.78 | 24.93 | 21.46 | 23.33 |
| Replicate 1 Call | A | A | A | A | A | A |
| Replicate 2 | 12.67 | 28.98 | 21.14 | 15.19 | 35.21 | 19.85 |
| Replicate 2 Call | A | A | A | A | A | A |
| Replicate 3 | 18.47 | 39.48 | 17.95 | 20.45 | 21.14 | 34.14 |
| Replicate 3 Call | A | A | A | A | A | A |
| Mean | 17.1 | 38.4 | 30.96 | 20.19 | 25.94 | 25.77 |
| Standard Deviation | 3.92 | 8.93 | 19.83 | 4.88 | 8.03 | 7.45 |
| Log2 Mean | 4.07 | 5.24 | 4.77 | 4.31 | 4.65 | 4.65 |
| Log2 Standard Deviation | 0.36 | 0.35 | 0.85 | 0.36 | 0.42 | 0.4 |