MOUSE GENE INFORMATION [PubMed]
Description | Ly6/Plaur domain containing 1 | ||||||||||||
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Synonyms | Lynx2; C530008O16Rik; 2700050C12Rik | ||||||||||||
Chromosome | 1 | ||||||||||||
Genetic Map Distance | 54.70 cM | ||||||||||||
RefSeq Accessions | NM_145100; NP_659568 | ||||||||||||
NCBI Entrez Gene | 72585 at chr1:127768616-127808791 (mm9) / chr1:125871408-125913171 (mm10) | ||||||||||||
Ensembl Gene | ENSMUSG00000026344 | ||||||||||||
VEGA Gene | OTTMUSG00000030265 | ||||||||||||
MGI Gene | MGI:1919835 | ||||||||||||
Mouse Protein (2) |
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Pfam Domains | |||||||||||||
Mouse alleles (4) |
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Human Homolog | LYPD1 (LY6/PLAUR domain containing 1) | ||||||||||||
Human synonyms | LYPDC1; PHTS | ||||||||||||
Human cytoband | 2q21.2 | ||||||||||||
Known deafness gene | No | ||||||||||||
Within mapped deafness loci | DFNB58 | ||||||||||||
Associated Human Disease in OMIM |
None
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Chicken homolog (2) |
ENSGALG00000012176 (LYPD1) encoding ENSGALP00000019856
ENSGALG00000012176 (LYPD1) encoding ENSGALP00000037073
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Gene Ontology
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FACS-Sorted Hair Cells
Data |
Chart

E16a |
E16b |
P0 |
P4 |
P7 |
P16 |
|
---|---|---|---|---|---|---|
Utricle GFP+ cells |
13 |
1 |
0 |
11 |
1 |
19 |
Cochlea GFP+ cells |
3 |
6 |
12 |
0 |
0 |
NA |
Utricle GFP- cells |
2 |
2 |
16 |
0 |
0 |
0 |
Cochlea GFP- cells |
9 |
16 |
6 |
37 |
105 |
NA |
Analysis
Condition A |
Mean A |
Condition B |
Mean B |
Fold Change (B/A) |
False Discovery Rate (FDR) |
---|---|---|---|---|---|
GFP- |
17 |
GFP+ |
6 |
0.35 |
0.425 |
Utricle |
5 |
Cochlea |
19 |
3.49 |
0.65 |
Embryonic |
6 |
Postnatal |
15 |
2.15 |
0.721 |
Adult Cochlear Inner and Outer Hair Cells
Probeset ID | IHC (mean ± sd) | OHC (mean ± sd) [OHC replicate] | Fold Change (OHC/IHC) | False Discovery Rate (FDR) |
---|---|---|---|---|
17226435 | 16.50 ± 1.63 | 19.45 ± 1.50 [20.85] | 1.18 | 0.504 |
Otic Progenitor Cells
Data
Growth Factor |
Replicate 1 |
Replicate 2 |
Replicate 3 |
Mean |
---|---|---|---|---|
bFGF |
11 |
11 |
12 |
8 |
No bFGF |
18 |
13 |
28 |
18 |
EGF |
36 |
41 |
42 |
40 |
Analysis
Condition A |
Mean A |
Condition B |
Mean B |
Fold Change (B/A) |
False Discovery Rate (FDR) |
---|---|---|---|---|---|
bFGF |
8 |
No bFGF |
18 |
2.03 |
1 |
bFGF |
8 |
EGF |
40 |
4.52 |
4.4e-6 |
No bFGF |
18 |
EGF |
40 |
2.23 |
0.00305 |
Chicken Stereocilium Proteomics
The chicken protein was not reproducibly detected in the chicken stereocilia. |
Auditory and Vestibular Ganglion Neurons
Probe set ID: 1431569_a_at
Age | E12 | E13 | E16 | P0 | P6 | P15 |
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Spiral ganglion | ||||||
Replicate 1 | 497.11 | 961.3 | 3471.95 | 3110.78 | 2142.68 | 1771.72 |
Replicate 1 Call | P | P | P | P | P | P |
Replicate 2 | 485.51 | 989.02 | 3491.66 | 1895.73 | 3344.31 | 1330.07 |
Replicate 2 Call | P | P | P | P | P | P |
Replicate 3 | 528.5 | 1229.64 | 2074.3 | 3794.83 | 827.35 | 3887.52 |
Replicate 3 Call | P | P | P | P | P | P |
Replicate 4 | 3280.35 | 3857.92 | 546.57 | 3925 | ||
Replicate 4 Call | P | P | P | P | ||
Mean | 503.71 | 1059.99 | 3079.57 | 3164.82 | 1715.23 | 2728.58 |
Standard Deviation | 22.24 | 147.58 | 676.92 | 911.19 | 1289.79 | 1371.86 |
Log2 Mean | 8.98 | 10.04 | 11.56 | 11.57 | 10.39 | 11.26 |
Log2 Standard Deviation | 0.06 | 0.19 | 0.36 | 0.48 | 1.21 | 0.8 |
Vestibular ganglion | ||||||
Replicate 1 | 954.68 | 1684.45 | 762.79 | 652.45 | 543.95 | 2427.03 |
Replicate 1 Call | P | P | P | P | P | P |
Replicate 2 | 906.03 | 1401.4 | 1011.01 | 817.63 | 723.88 | 2378.72 |
Replicate 2 Call | P | P | P | P | P | P |
Replicate 3 | 849.69 | 1576.26 | 442.65 | 950.92 | 646.51 | 2168.25 |
Replicate 3 Call | P | P | P | P | P | P |
Mean | 903.47 | 1554.04 | 738.82 | 807 | 638.11 | 2324.67 |
Standard Deviation | 52.54 | 142.83 | 284.94 | 149.52 | 90.26 | 137.6 |
Log2 Mean | 9.82 | 10.6 | 9.45 | 9.64 | 9.31 | 11.18 |
Log2 Standard Deviation | 0.08 | 0.13 | 0.61 | 0.27 | 0.21 | 0.09 |