MOUSE GENE INFORMATION [PubMed]
| Description | ankyrin repeat and KH domain containing 1 | ||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Synonyms | 1110004O12Rik; 9130019P20Rik; A530027J04Rik; 4933432B13Rik | ||||||||||||||||||||||||||||
| Chromosome | 18 | ||||||||||||||||||||||||||||
| Genetic Map Distance | 19.46 cM | ||||||||||||||||||||||||||||
| RefSeq Accessions | NM_175375; NP_780584 | ||||||||||||||||||||||||||||
| NCBI Entrez Gene | 108857 at chr18:36720257-36818562 (mm9) / chr18:36560603-36658908 (mm10) | ||||||||||||||||||||||||||||
| Ensembl Gene | ENSMUSG00000024483 | ||||||||||||||||||||||||||||
| VEGA Gene | OTTMUSG00000034846 | ||||||||||||||||||||||||||||
| MGI Gene | MGI:1921733 | ||||||||||||||||||||||||||||
| Mouse Protein (6) |
|
||||||||||||||||||||||||||||
| Pfam Domains | |||||||||||||||||||||||||||||
| Mouse alleles (2) |
|
||||||||||||||||||||||||||||
| Human Homolog | ANKHD1 (ankyrin repeat and KH domain containing 1) | ||||||||||||||||||||||||||||
| Human synonyms | MASK; VBARP | ||||||||||||||||||||||||||||
| Human cytoband | 5q31.3 | ||||||||||||||||||||||||||||
| Known deafness gene | No | ||||||||||||||||||||||||||||
| Within mapped deafness loci | No | ||||||||||||||||||||||||||||
| Associated Human Disease in OMIM |
None
|
||||||||||||||||||||||||||||
| Chicken homolog (1) |
ENSGALG00000001099 (ANKHD1-EIF4EBP3) encoding ENSGALP00000001645
|
||||||||||||||||||||||||||||
|
Gene Ontology
|
|
FACS-Sorted Hair Cells
Ankhd1 is not detected by RNA-Seq.
Adult Cochlear Inner and Outer Hair Cells
| Probeset ID | IHC (mean ± sd) | OHC (mean ± sd) [OHC replicate] | Fold Change (OHC/IHC) | False Discovery Rate (FDR) |
|---|---|---|---|---|
| 17349671 | 104.83 ± 4.48 | 104.61 ± 2.09 [103.00] | 1.00 | 0.986 |
| 17349713 | 99.70 ± 37.81 | 70.04 ± 137.95 [363.97] | 0.70 | 0.645 |
| 17349715 | 24.68 ± 1.68 | 27.51 ± 3.21 [31.94] | 1.11 | 0.586 |
Otic Progenitor Cells
Ankhd1 is not detected by RNA-Seq.
Chicken Stereocilium Proteomics
| The chicken protein was not reproducibly detected in the chicken stereocilia. |
Auditory and Vestibular Ganglion Neurons
Probe set ID: 1448008_at
| Age | E12 | E13 | E16 | P0 | P6 | P15 |
|---|---|---|---|---|---|---|
| Spiral ganglion | ||||||
| Replicate 1 | 483.17 | 61.35 | 292.55 | 178.9 | 59.06 | 151.23 |
| Replicate 1 Call | P | P | P | M | A | P |
| Replicate 2 | 522.49 | 76.56 | 629.64 | 172.29 | 163.85 | 280.77 |
| Replicate 2 Call | P | P | P | A | P | M |
| Replicate 3 | 509.12 | 142 | 433.21 | 159.47 | 181.8 | 367 |
| Replicate 3 Call | P | P | P | A | P | A |
| Replicate 4 | 850.53 | 151.35 | 262.24 | 87.89 | ||
| Replicate 4 Call | P | M | A | A | ||
| Mean | 504.93 | 93.3 | 551.48 | 165.5 | 166.74 | 221.72 |
| Standard Deviation | 19.99 | 42.85 | 242.61 | 12.41 | 83.57 | 125.79 |
| Log2 Mean | 8.98 | 6.45 | 9 | 7.37 | 7.2 | 7.59 |
| Log2 Standard Deviation | 0.06 | 0.63 | 0.67 | 0.11 | 0.92 | 0.92 |
| Vestibular ganglion | ||||||
| Replicate 1 | 487.87 | 118.1 | 151.14 | 55.36 | 65.4 | 66.28 |
| Replicate 1 Call | P | P | A | A | A | P |
| Replicate 2 | 533.61 | 226.16 | 72.76 | 64.61 | 108.06 | 76 |
| Replicate 2 Call | P | P | A | A | A | A |
| Replicate 3 | 489.01 | 166.81 | 68.21 | 73.66 | 52.69 | 81.97 |
| Replicate 3 Call | P | P | A | A | A | A |
| Mean | 503.5 | 170.36 | 97.37 | 64.54 | 75.38 | 74.75 |
| Standard Deviation | 26.09 | 54.12 | 46.62 | 9.15 | 29 | 7.92 |
| Log2 Mean | 8.97 | 7.36 | 6.51 | 6 | 6.17 | 6.22 |
| Log2 Standard Deviation | 0.07 | 0.47 | 0.64 | 0.21 | 0.53 | 0.16 |