MOUSE GENE INFORMATION [PubMed]
Description | actin, gamma, cytoplasmic 1 | ||||||||||||||||||||||||||||||||
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Synonyms | Actl; E51 | ||||||||||||||||||||||||||||||||
Chromosome | 11 | ||||||||||||||||||||||||||||||||
Genetic Map Distance | 84.07 cM | ||||||||||||||||||||||||||||||||
RefSeq Accessions | NM_009609; NP_033739 | ||||||||||||||||||||||||||||||||
NCBI Entrez Gene | 11465 at chr11:120207004-120209798 (mm9) / chr11:120345690-120348484 (mm10) | ||||||||||||||||||||||||||||||||
Ensembl Gene | ENSMUSG00000062825 | ||||||||||||||||||||||||||||||||
VEGA Gene | OTTMUSG00000004137 | ||||||||||||||||||||||||||||||||
MGI Gene | MGI:87906 | ||||||||||||||||||||||||||||||||
Mouse Protein (7) |
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Pfam Domains | |||||||||||||||||||||||||||||||||
Mouse alleles (4) |
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Human Homolog | ACTG1 (actin, gamma 1) | ||||||||||||||||||||||||||||||||
Human synonyms | ACT; ACTG; DFNA20; DFNA26 | ||||||||||||||||||||||||||||||||
Human cytoband | 17q25 | ||||||||||||||||||||||||||||||||
Known deafness gene | DFNA20/26 | ||||||||||||||||||||||||||||||||
Within mapped deafness loci | No | ||||||||||||||||||||||||||||||||
Associated Human Disease in OMIM | |||||||||||||||||||||||||||||||||
Chicken homolog (1) |
ENSGALG00000009621 (ACTG1) encoding ENSGALP00000015657
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Gene Ontology
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FACS-Sorted Hair Cells
Data |
Chart

E16a |
E16b |
P0 |
P4 |
P7 |
P16 |
|
---|---|---|---|---|---|---|
Utricle GFP+ cells |
28788 |
7610 |
13834 |
21629 |
16758 |
8798 |
Cochlea GFP+ cells |
33384 |
13375 |
18427 |
24038 |
21240 |
NA |
Utricle GFP- cells |
15290 |
9489 |
9365 |
22165 |
11106 |
5837 |
Cochlea GFP- cells |
19419 |
6075 |
7884 |
11821 |
18519 |
NA |
Analysis
Condition A |
Mean A |
Condition B |
Mean B |
Fold Change (B/A) |
False Discovery Rate (FDR) |
---|---|---|---|---|---|
GFP- |
12452 |
GFP+ |
18898 |
1.52 |
0.807 |
Utricle |
14222 |
Cochlea |
17418 |
1.22 |
1 |
Embryonic |
16679 |
Postnatal |
15102 |
0.91 |
1 |
Adult Cochlear Inner and Outer Hair Cells
Probeset ID | IHC (mean ± sd) | OHC (mean ± sd) [OHC replicate] | Fold Change (OHC/IHC) | False Discovery Rate (FDR) |
---|---|---|---|---|
17273061 | 23.57 ± 2.06 | 30.03 ± 5.54 [41.40] | 1.27 | 0.501 |
17547608 | 785.58 ± 26.86 | 511.65 ± 165.44 [770.77] | 0.65 | 0.501 |
Otic Progenitor Cells
Data
Growth Factor |
Replicate 1 |
Replicate 2 |
Replicate 3 |
Mean |
---|---|---|---|---|
bFGF |
18486 |
17842 |
19726 |
31367 |
No bFGF |
17461 |
18569 |
19440 |
26731 |
EGF |
33659 |
31803 |
35729 |
33730 |
Analysis
Condition A |
Mean A |
Condition B |
Mean B |
Fold Change (B/A) |
False Discovery Rate (FDR) |
---|---|---|---|---|---|
bFGF |
31367 |
No bFGF |
26731 |
0.85 |
1 |
bFGF |
31367 |
EGF |
33730 |
1.08 |
0.579 |
No bFGF |
26731 |
EGF |
33730 |
1.26 |
0.0464 |
Chicken Stereocilium Proteomics
Protein ID | ENSGALP00000015657 |
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Symbol | ACTB |
Description | Actin, beta |
log10 riBAQ in stereocilia (mean ± sd) | -0.57 ± 0.05 |
log10 riBAQ in utricle (mean ± sd) | -1.41 ± 0.06 |
Molecules per stereocilium (mean ± error with slope error) | 400000.00 ± 34094.75 |
Corrected Molecules per stereocilium (mean ± sd) | 400000.11 ± 48441.88 |
Stereocilium / Utricle ratio (mean ± sd) | 6.98 ± 0.70 |
Enriched in the stereocilia (FDR < 0.05) | TRUE |
Auditory and Vestibular Ganglion Neurons
Probe set ID: 1415779_s_at
Age | E12 | E13 | E16 | P0 | P6 | P15 |
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Spiral ganglion | ||||||
Replicate 1 | 9072.26 | 7152.07 | 8623.41 | 8666.51 | 7013.63 | 7445.72 |
Replicate 1 Call | P | P | P | P | P | P |
Replicate 2 | 9249.56 | 8501.51 | 7073.37 | 8169.16 | 8360.07 | 5880.46 |
Replicate 2 Call | P | P | P | P | P | P |
Replicate 3 | 9632.8 | 8944.46 | 7713.59 | 8440.1 | 7125.98 | 6550 |
Replicate 3 Call | P | P | P | P | P | P |
Replicate 4 | 6528.09 | 8465.12 | 7110.55 | 6458.97 | ||
Replicate 4 Call | P | P | P | P | ||
Mean | 9318.21 | 8199.35 | 7484.62 | 8435.22 | 7402.56 | 6583.79 |
Standard Deviation | 286.51 | 933.62 | 900.62 | 204.29 | 640.28 | 646.61 |
Log2 Mean | 13.19 | 12.99 | 12.86 | 13.04 | 12.85 | 12.68 |
Log2 Standard Deviation | 0.04 | 0.17 | 0.17 | 0.04 | 0.12 | 0.14 |
Vestibular ganglion | ||||||
Replicate 1 | 9574.74 | 9270.31 | 7647.68 | 7853.5 | 5717.23 | 6364.92 |
Replicate 1 Call | P | P | P | P | P | P |
Replicate 2 | 9053.57 | 9007.86 | 7478.37 | 6906.47 | 7419.28 | 6089.59 |
Replicate 2 Call | P | P | P | P | P | P |
Replicate 3 | 9471.67 | 8959.77 | 6386.76 | 7194.38 | 7246.37 | 6294.09 |
Replicate 3 Call | P | P | P | P | P | P |
Mean | 9366.66 | 9079.31 | 7170.94 | 7318.12 | 6794.29 | 6249.53 |
Standard Deviation | 276 | 167.15 | 684.37 | 485.49 | 936.76 | 142.97 |
Log2 Mean | 13.19 | 13.15 | 12.8 | 12.84 | 12.72 | 12.61 |
Log2 Standard Deviation | 0.04 | 0.03 | 0.14 | 0.09 | 0.21 | 0.03 |