MOUSE GENE INFORMATION [PubMed]
| Description | solute carrier family 44, member 4 | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Synonyms | NG22; 2210409B01Rik | ||||||||||||||||
| Chromosome | 17 | ||||||||||||||||
| Genetic Map Distance | 18.46 cM | ||||||||||||||||
| RefSeq Accessions | NM_023557; NP_076046 | ||||||||||||||||
| NCBI Entrez Gene | 70129 at chr17:35051411-35067381 (mm9) / chr17:34914239-34930436 (mm10) | ||||||||||||||||
| Ensembl Gene | ENSMUSG00000007034 | ||||||||||||||||
| VEGA Gene | OTTMUSG00000037275 | ||||||||||||||||
| MGI Gene | MGI:1917379 | ||||||||||||||||
| Mouse Protein (3) |
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| Pfam Domains | Pfam-B_2322; Choline_transpo | ||||||||||||||||
| Mouse alleles (4) |
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| Human Homolog | SLC44A4 (solute carrier family 44, member 4) | ||||||||||||||||
| Human synonyms | C6orf29; CTL4; NG22 | ||||||||||||||||
| Human cytoband | 6p21.3 | ||||||||||||||||
| Known deafness gene | No | ||||||||||||||||
| Within mapped deafness loci | DFNA21; DFNA31; OTSC3 | ||||||||||||||||
| Associated Human Disease in OMIM |
None
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| Chicken homolog (0) |
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Gene Ontology
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FACS-Sorted Hair Cells
Data |
Chart
E16a |
E16b |
P0 |
P4 |
P7 |
P16 |
|
|---|---|---|---|---|---|---|
Utricle GFP+ cells |
8 |
0 |
5 |
4 |
0 |
19 |
Cochlea GFP+ cells |
0 |
36 |
1 |
0 |
2 |
NA |
Utricle GFP- cells |
0 |
7 |
5 |
43 |
0 |
0 |
Cochlea GFP- cells |
6 |
0 |
0 |
3 |
8 |
NA |
Analysis
Condition A |
Mean A |
Condition B |
Mean B |
Fold Change (B/A) |
False Discovery Rate (FDR) |
|---|---|---|---|---|---|
GFP- |
7 |
GFP+ |
7 |
1.04 |
0.958 |
Utricle |
7 |
Cochlea |
6 |
0.76 |
1 |
Embryonic |
7 |
Postnatal |
6 |
0.90 |
1 |
Adult Cochlear Inner and Outer Hair Cells
| Probeset ID | IHC (mean ± sd) | OHC (mean ± sd) [OHC replicate] | Fold Change (OHC/IHC) | False Discovery Rate (FDR) |
|---|---|---|---|---|
| 17336788 | 15.83 ± 0.21 | 15.50 ± 0.13 [15.68] | 0.98 | 0.504 |
Otic Progenitor Cells
Data
Growth Factor |
Replicate 1 |
Replicate 2 |
Replicate 3 |
Mean |
|---|---|---|---|---|
bFGF |
0 |
0 |
1 |
0 |
No bFGF |
0 |
2 |
1 |
0 |
EGF |
0 |
0 |
2 |
1 |
Analysis
Condition A |
Mean A |
Condition B |
Mean B |
Fold Change (B/A) |
False Discovery Rate (FDR) |
|---|---|---|---|---|---|
bFGF |
0 |
No bFGF |
0 |
1.73 |
1 |
bFGF |
0 |
EGF |
1 |
2.05 |
0.877 |
No bFGF |
0 |
EGF |
1 |
1.18 |
1 |
Chicken Stereocilium Proteomics
No chicken homolog has been identified for Slc44a4.
Auditory and Vestibular Ganglion Neurons
Probe set ID: 1416596_at
| Age | E12 | E13 | E16 | P0 | P6 | P15 |
|---|---|---|---|---|---|---|
| Spiral ganglion | ||||||
| Replicate 1 | 19.57 | 25.46 | 24.07 | 37.94 | 28.61 | 21.06 |
| Replicate 1 Call | A | A | A | A | A | A |
| Replicate 2 | 28.87 | 25.94 | 23.44 | 26.32 | 13.57 | 7.19 |
| Replicate 2 Call | A | A | A | A | A | A |
| Replicate 3 | 34.54 | 15.43 | 1 | 42.61 | 41.49 | 42.44 |
| Replicate 3 Call | A | A | A | A | A | A |
| Replicate 4 | 1 | 40.13 | 51.15 | 16.83 | ||
| Replicate 4 Call | A | A | A | A | ||
| Mean | 27.66 | 22.28 | 12.38 | 36.75 | 33.71 | 21.88 |
| Standard Deviation | 7.56 | 5.93 | 13.14 | 7.21 | 16.29 | 14.88 |
| Log2 Mean | 4.75 | 4.44 | 2.29 | 5.18 | 4.91 | 4.18 |
| Log2 Standard Deviation | 0.42 | 0.43 | 2.64 | 0.31 | 0.84 | 1.06 |
| Vestibular ganglion | ||||||
| Replicate 1 | 13 | 31.13 | 32.32 | 45.82 | 38.22 | 37.57 |
| Replicate 1 Call | A | A | A | A | A | A |
| Replicate 2 | 21.37 | 23.07 | 20.83 | 42.48 | 75.55 | 30.48 |
| Replicate 2 Call | A | A | A | A | A | A |
| Replicate 3 | 20.29 | 23.69 | 31.19 | 41.32 | 37.94 | 41.32 |
| Replicate 3 Call | A | A | A | A | A | A |
| Mean | 18.22 | 25.96 | 28.11 | 43.21 | 50.57 | 36.46 |
| Standard Deviation | 4.55 | 4.49 | 6.33 | 2.34 | 21.63 | 5.51 |
| Log2 Mean | 4.15 | 4.68 | 4.79 | 5.43 | 5.58 | 5.18 |
| Log2 Standard Deviation | 0.39 | 0.24 | 0.35 | 0.08 | 0.57 | 0.22 |